I ususally take one tablet of melatonin 5mg at night at around 10pm. Sometimes I can't catch sleep and I take another tablet at 12pm. Does this harm my circadian rhythm? In general, does such a high dose harmful for my system?
No, it isn't harmful for your system, because the individual need for melatonin varies very much from person to person. It also doesn't affect your circadian rhythm since you take the tablet at the right time for your pineal gland to respond to it.

User: KeyMelatonin.com

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